ABSTRACT
We conducted a retrospective chart review for all 42 patients, 9 males and 33 females, diagnosed with juvenile idiopathic oligoarthritis between July 1995 and October 2004 at the paediatric rheumatology clinic in King Hussein Medical Centre. Age range was 1.2- 15.2 years, mean 3.6 [standard deviation 2.4] years. Of those < 6 years, 80% were females. Most patients [64%] had monoarthritis; the knee was the most common joint affected [71%]. Two patients had developed extended oligoarthritis Nine [21%] had asymptomatic uveitis: 6 females [P = 0.350], 7 [77%] < 3 years of age [P= 0.301].and 7 [77%] with antinuclear antibodies [ANAs] [P = 0.071]. Eighteen [43%] females were positive for ANAs. Most patients had undergone unnecessary, lengthy work- up and treatment before diagnosis
Subject(s)
Female , Humans , Male , Uveitis , Antibodies, Antinuclear , AwarenessABSTRACT
Familial Mediterranean fever is quite prevalent among Arabs. We reviewed the files of 56 patients diagnosed with familial Mediterranean fever and followed up at King Hussein Medical Centre in Jordan over 4 years for their clinical profile, course, genotype, treatment and complications. There were 30 males and 26 females with a mean age at onset of 5.2 years. Abdominal pain [79%] was the commonest manifestation, followed by arthritis [13%] and chest pain [4%]. Family history was positive in 50% of patients. Regarding treatment, 97% of patients responded well to colchicine, and amyloidosis was not documented in any patients after 5 years follow- up. The commonest genotype was M694 [64%], followed by heterozygous M694V- V726A [23%] and E148Q [8%]